While most cases of cancer happen by chance due to a variety of factors, about 10% of the time, cancer is linked to a single change in a gene, or mutation, that has been passed down from generation to generation. This is referred to as hereditary cancer.
Families with hereditary cancer often have multiple family members affected with cancer, and certain cancers may be diagnosed at younger ages. A person who has inherited a gene mutation associated with hereditary cancer will not necessarily get cancer, but he or she is at a higher risk than those without a gene mutation.
The Myriad myRisk hereditary cancer panel can help determine if you carry a mutation that would put you at an increased risk for cancer.
Myriad myRisk can determine whether you are at an increased risk of certain cancers.
The cancer patterns in your family will help your provider determine your risks and options. Before your next appointment, try to gather whatever information you can about your relatives on both sides of your family who have been affected by cancer.
- You’ll need to know the type of cancer they had and at what age they were diagnosed
- If you or anyone in your family has had colon polyps (growths found during a colonoscopy), your provider will want to know about that too
- If you think anyone in your family might have already had genetic testing for cancer, it’s helpful if you can provide that information, including the genes they were tested for and the results
Possible results of the myRisk Hereditary Cancer Test
A negative result from genetic testing does not mean that you will never develop cancer. You may still be at risk, especially if you have a strong personal or family history of the disease. If you have a negative result, your healthcare provider may still advise that additional cancer screening is appropriate for you and your family.
Variant of uncertain significance
Sometimes a change is identified in a gene, but there is limited scientific evidence that it increases risk for cancer. These types of changes are called variants of uncertain significance and they are quite common. Professional societies recommend that variants of uncertain significance be treated as negative results when it comes to making clinical decisions.
A positive result is not a diagnosis of cancer, nor is it a guarantee that you will develop the disease. A positive result means only that there is a mutation in one of the genes tested that is known to cause an increased chance of developing one or more types of cancer over your lifetime. With this knowledge, you’ll have the chance to work with your healthcare provider to develop a prevention and/or treatment program.
Myriad myRisk looks at 29 genes associated with risk for many different kinds of cancer, such as breast, ovarian, colon, pancreatic, prostate, and others. Your healthcare provider can help you determine if testing is right for you.
Myriad is in-network with 97% of private insurance plans. We also have financial assistance and payment plans to help you handle a high deductible if you have one. Myriad myRisk must be ordered by a healthcare provider. A small sample of your saliva or blood is all that’s needed and results are ready in about two weeks on average.
Myriad myRisk focuses on genes with clear cancer risks and patient management guidelines. The platform we use is scientifically validated and meets the highest industry standards, with >99.92% sensitivity, specificity, and accuracy—so you can feel confident in your results and the decisions you make.
Myriad’s patient-centered site, mySupport360, is dedicated to promoting awareness, sharing educational content and providing support for hereditary cancer.